产品货号：
Z23765
中文名称：
PLEKHO1抗体
英文名称：
Anti-PLEKHO1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PLEKHO1 Antibody |
| 指标别名 | C Jun binding protein;CK2 interacting protein 1;CKIP 1;CKIP1;CKIP-1;HQ0024c;JBP;OC120;PLEKHO1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB |
| 基因名称 | PLEKHO1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | CKIP1 antibody was raised against an 18 amino acid synthetic peptide from near the carboxy terminus of human CKIP1.The immunogen is located within the last 50 amino acids of CKIP1. |
| 计算分子量 | 46kDa |
| 成分 | CKIP1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | CKIP1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | CKIP1 was identified through a yeast-two hybrid screening as a protein that would interact with only one of the two catalytic subunits of the casein kinase 2 complex.CKIP1 is a pleckstrin homology domain-containing protein localized within the nucleus and at the plasma membrane that interacts with CK2alpha but not CK2alpha',and is thought to play a role in targeting CK2alpha to a particular cellular location.CKIP1 has been implicated in muscle differentiation and the regulation of cell morphology and actin cytoskeleton.CKIP1 can also interact with other proteins such as ATM,an upstream kinase of p53,and recruit the nuclear ATM to the plasma membrane,suggesting CKIP1 may regulate ATM function through re-localizing ATM.CKIP1 can also form a complex with the kinase AKT,leading to a down-regulation of PI3K/AKT signaling and suppression of tumor growth in vivo. |
| Uniprot ID | Q53GL0 |
| 基因名全称 | Pleckstrin homology domain containing,family O member 1 |
| 蛋白名全称 | Pleckstrin homology domain containing,family O member 1 |
| 推荐稀释比 | CKIP1 antibody can be used for detection of CKIP1 by Western blot at 1 ～ 2μg/mL.Antibody validated:Western Blot in human samples.All other applications and species not yet tested. |
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